LPLexPort

Free CPN Practice Test — Certified Pediatric Nurse

You must master 150 scored items to earn your credential. Start your review with these Pediatric Nursing Certification Board (PNCB) CPN practice questions. They cover all four official domains, from Assessment to Health Promotion, before you tackle our full bank of 2,200+ practice questions.

Written and reviewed by the LexPort exam-prep team, led by our Founder & Exam-Prep Lead. LexPort builds certification practice questions — this is exam-preparation material, not medical advice. Last reviewed June 2026.

Try 5 CPN questions

Scored as you go, with every answer explained. No signup.

Question 1 of 5★ 0/5

The parents of a 2-week-old newborn are distressed after newborn screening results indicate the infant has sickle cell trait. The parents are distressed and ask what treatments their baby needs right now.

Pick an answer

Prefer a longer set? Full practice quiz →

CPN exam at a glance

Official figures from PNCB, checked October 2026.

Exam
175 questions (150 scored), 180 minutessource
Cost
$309, including $103 registrationsource
Retakes
$252 re-exam, new 90-day windowsource
Pass rate
71.39% first-time pass rate (2025)source
Where you test
PSI: 300+ centers or live remotesource

Test yourself: 3 CPN practice questions

Tap an answer for instant feedback and the full rationale. The app has 2,200+, timed and scored.

Question 1

A 17-year-old female with Crohn's disease and a recent ileostomy asks the nurse about returning to high school and attending the upcoming prom. Which intervention is the priority?

▸ Why C is the answer

A recent ileostomy represents a major alteration in body image, especially for an older adolescent navigating identity and dating. Option C is the most appropriate response because it proactively opens the door to discuss fears about intimacy and body image. Teens often worry about how visible medical devices will affect romantic relationships but may feel too embarrassed to bring it up themselves. Option A focuses only on the mechanical task of pouch management, missing the deeper psychosocial cues about prom and social reintegration. Option B suggests hiding the appliance, which can inadvertently reinforce feelings of shame rather than promoting acceptance. Option D encourages avoidance and isolation, which directly hinders her psychosocial development and transition back to normal adolescent activities. Addressing sexual identity concerns is a critical component of holistic care.

🔑 Key takeaway

Older adolescents with new visible medical devices require proactive assessment regarding sexual identity and intimacy concerns.

Question 2

An 18-month-old requires a postoperative dressing change on their abdomen. Which strategy should the nurse use to prepare the child right before the procedure begins?

▸ Why C is the answer

At 18 months, children are in the sensorimotor stage and learn about their environment through touching and seeing. Allowing immediate physical contact with safe, non-threatening equipment like clean bandages demystifies the objects and reduces fear through sensorimotor exploration. Option A is incorrect because coloring books about healing are too abstract for this age. Option B relies on anatomical charts, which exceed a toddler's cognitive capacity. Option D is better suited for older preschoolers or school-aged children who can benefit from peer modeling.

🔑 Key takeaway

Toddlers learn through sensorimotor exploration, so handling safe equipment immediately before a procedure reduces fear.

Question 3

A 14-year-old patient with confirmed acute appendicitis and a documented severe anaphylactic penicillin allergy is ordered to receive preoperative antibiotics. Which action should the nurse take to ensure safe medication administration?

▸ Why C is the answer

A severe anaphylactic penicillin allergy strictly contraindicates the use of beta-lactam antibiotics like piperacillin-tazobactam and requires extreme caution with cephalosporins like ceftriaxone due to potential cross-reactivity. Verifying an order for intravenous ciprofloxacin and intravenous metronidazole provides appropriate broad-spectrum gram-negative and anaerobic coverage safely. Administering piperacillin-tazobactam or infusing ceftriaxone places the patient at high risk for a life-threatening anaphylactic reaction. Requesting oral amoxicillin-clavulanate is incorrect because it is a penicillin derivative and inappropriate for a patient who must remain NPO for surgery.

🔑 Key takeaway

Patients with severe penicillin allergies require non-beta-lactam antibiotic alternatives preoperatively to prevent anaphylaxis.

Question 1

The parents of a 2-week-old newborn are distressed after newborn screening results indicate the infant has sickle cell trait. The parents are distressed and ask what treatments their baby needs right now.

  • A) Explain the infant needs lifelong daily prophylactic oral folic acid supplementation.
  • B) Clarify the infant is a healthy carrier and will not develop disease.✓
  • C) Schedule the infant for baseline hemoglobin electrophoresis testing at six months.
  • D) Refer the family to a pediatric hematologist for immediate chronic disease management.

💡 Key Takeaway

Sickle cell trait is a benign carrier state requiring parental reassurance rather than medical intervention.

Show rationale

Newborn screening reliably identifies sickle cell trait, which frequently causes profound parental anxiety due to confusion with the actual disease. The primary nursing action is to provide clear education that the trait is a benign carrier state and the child will not develop sickle cell disease. Options A and D involve interventions and referrals that are standard for managing sickle cell disease, not the trait, and would unnecessarily elevate parental fear. Option C is redundant and unnecessary because the newborn screening has already confirmed the diagnosis using highly sensitive methods like electrophoresis or high-performance liquid chromatography.

Question 2

A 12-month-old infant presents for a well-child visit. The immunization registry indicates the infant received DTaP at 2 and 4 months of age but missed the 6-month dose. How should the pediatric nurse practitioner proceed with the DTaP series?

  • A) Restart the primary series with the first dose.
  • B) Administer the third dose and schedule the fourth.✓
  • C) Administer the third dose and skip the fourth.
  • D) Restart the primary series using the DT formulation.

💡 Key Takeaway

Interrupted vaccine schedules do not require restarting; simply administer the next dose in the series.

Show rationale

Administering the third dose and scheduling the fourth is the correct approach. When a vaccine schedule is interrupted, you do not need to restart the series, making any option that suggests restarting completely incorrect. The infant's immune system retains memory of the first two doses. You simply pick up where the schedule left off by giving the missed third dose today. Skipping the fourth dose is incorrect because a complete primary series requires four doses of DTaP before age two to achieve optimal immunity. Using the DT formulation is incorrect because the child needs pertussis protection, and DT is only indicated if a severe contraindication to the pertussis antigen exists.

Question 3

A 15-month-old toddler who was born at 26 weeks gestation comes to the clinic in October. The child has bronchopulmonary dysplasia and requires daily inhaled corticosteroids. The nurse practitioner is planning preventive care for the upcoming winter season. Which respiratory syncytial virus prophylaxis plan is most appropriate?

  • A) Administer nirsevimab due to chronic lung disease.✓
  • B) Withhold prophylaxis as age exceeds twelve months.
  • C) Provide palivizumab only if oxygen is required.
  • D) Delay prophylaxis until acute respiratory symptoms start.

💡 Key Takeaway

High-risk toddlers with chronic lung disease of prematurity require RSV prophylaxis during their second respiratory season.

Show rationale

The latest guidelines recommend that children up to nineteen months of age who have chronic lung disease of prematurity and require medical support like corticosteroids or diuretics within six months of the respiratory syncytial virus season should receive prophylaxis. Nirsevimab is the preferred long-acting monoclonal antibody for this high-risk group entering their second respiratory season. Option B is incorrect because high-risk infants with chronic lung disease remain eligible past twelve months of age. Option C is incorrect because medical support includes inhaled corticosteroids and does not strictly require active oxygen therapy to qualify for prophylaxis. Option D is incorrect because monoclonal antibodies provide passive immunity and must be administered preventatively before exposure rather than waiting for acute respiratory symptoms to develop.

Question 4

An infant born at 30 weeks gestation is now two months chronological age. The infant has a history of bronchopulmonary dysplasia and demonstrates poor weight gain on standard formula. The nurse practitioner reviews the infant's current nutritional plan to support optimal catch-up growth. Which intervention is most appropriate?

  • A) Switch to a standard soy based liquid formula.
  • B) Increase the daily volume of standard infant formula.
  • C) Introduce early solid foods to boost caloric intake.
  • D) Transition to a twenty four calorie enriched formula.✓

💡 Key Takeaway

Premature infants with bronchopulmonary dysplasia often need higher-calorie formulas to meet increased metabolic demands for growth.

Show rationale

Infants with a history of prematurity and bronchopulmonary dysplasia have significantly higher metabolic demands due to increased work of breathing and the need for lung tissue repair. When these infants show poor weight gain they typically require a higher caloric density to achieve appropriate catch-up growth. Transitioning to a twenty-four calorie per ounce enriched formula provides the necessary energy without requiring the infant to consume excessive fluid volumes. Option A is incorrect because soy formula does not provide the extra calories or specific nutrients needed for preterm catch-up growth. Option B is suboptimal because infants with chronic lung disease often cannot tolerate large fluid volumes due to the risk of pulmonary edema. Option C is incorrect because a two-month-old infant is not developmentally ready for solid foods and lacks the necessary oral motor skills.

Question 5

A neonate born at 34 weeks gestation is preparing for discharge from the neonatal intensive care unit. The discharge is scheduled for mid-November, and the infant is currently two weeks old. The nurse practitioner discusses respiratory syncytial virus prevention with the parents. Which action is most appropriate regarding prophylaxis?

  • A) Delay the immunization until reaching two months old.
  • B) Administer the immunization immediately prior to hospital discharge.✓
  • C) Schedule the immunization for the next respiratory season.
  • D) Withhold the immunization since gestation exceeds thirty weeks.

💡 Key Takeaway

All infants under eight months should receive RSV prophylaxis during or entering their first viral season.

Show rationale

Current pediatric guidelines recommend that all infants younger than eight months who are born during or are entering their first respiratory syncytial virus season should receive nirsevimab prophylaxis. Because this infant is discharging in November which is the peak of the viral season the most effective strategy is to administer the immunization shortly before hospital discharge. Option A is incorrect because waiting until two months of age leaves the vulnerable premature infant unprotected during the height of the season. Option C is incorrect as the infant is currently at immediate risk and needs protection for this current season rather than waiting a full year. Option D is incorrect because the updated guidelines expanded prophylaxis recommendations to include all infants entering their first season regardless of their specific gestational age at birth.

Question 6

A male infant born at 27 weeks gestation is evaluated at six months chronological age. The nurse practitioner plots his growth parameters and notes a rapidly increasing head circumference that has crossed two major percentiles on the adjusted growth chart, while his weight and length are increasing more gradually. His neurological examination is completely normal. How should the nurse practitioner interpret these findings?

  • A) Suspect hydrocephalus requiring an urgent pediatric neurology evaluation.
  • B) Attribute the rapid growth to excessive caloric intake.
  • C) Recognize this as expected early catch up growth.✓
  • D) Refer the infant for a comprehensive genetic workup.

💡 Key Takeaway

Catch-up growth in premature infants typically begins with rapid head circumference expansion followed by weight and length.

Show rationale

In extremely premature infants the pattern of catch-up growth typically follows a predictable sequence where head circumference accelerates first to support rapid brain development. This is usually followed by weight gain and eventually linear length growth. Because the infant has a completely normal neurological examination this rapid head growth represents a healthy and expected physiological response rather than a pathological condition. Option A is incorrect because without other signs of increased intracranial pressure like bulging fontanelles or developmental regression an urgent neurology referral is unnecessary. Option B is incorrect because excessive caloric intake would primarily manifest as rapid weight gain rather than isolated head circumference growth. Option D is incorrect because this specific growth trajectory is a standard hallmark of prematurity recovery and does not inherently suggest an underlying genetic syndrome requiring extensive investigation.

Question 7

A 14-year-old with sickle cell trait is joining the high school football team. The parents are concerned about the risk of sudden collapse during intense summer training and ask for guidance.

  • A) Restrict participation in high-intensity outdoor sports during the hottest summer months.
  • B) Provide prophylactic penicillin prior to engaging in strenuous outdoor summer activities.
  • C) Ensure frequent hydration breaks and gradual acclimatization to the summer heat.✓
  • D) Administer supplemental oxygen before and after intense outdoor summer practice sessions.

💡 Key Takeaway

Adolescents with sickle cell trait can play sports safely by prioritizing hydration and gradual heat acclimatization.

Show rationale

Individuals with sickle cell trait are generally asymptomatic but face increased risks of exercise-related complications, such as rhabdomyolysis or sudden death, under conditions of extreme exertion, dehydration, and high heat. The most effective preventative management is ensuring adequate hydration and allowing for gradual acclimatization to environmental stressors. Option A is an unnecessary restriction, as the trait does not preclude sports participation. Option B describes an intervention appropriate for sickle cell disease, not the trait. Option D is highly impractical and not indicated for routine prevention in individuals who merely carry the trait.

Question 8

A 16-year-old male with sickle cell trait presents to the clinic reporting painless, dark-colored urine for two days. He recently completed a strenuous hiking trip in a national park.

  • A) Reassure the adolescent that this is a normal physiological response to exercise.
  • B) Advise immediate fluid restriction to prevent further renal tubular fluid volume overload.
  • C) Initiate broad-spectrum antibiotics to treat a presumed severe urinary tract infection.
  • D) Evaluate the adolescent for exercise-induced gross hematuria or renal medullary complications.✓

💡 Key Takeaway

Extreme exertion in sickle cell trait can trigger renal complications like gross hematuria or papillary necrosis.

Show rationale

While sickle cell trait is largely benign, it can occasionally cause renal complications, particularly after extreme physical stress, dehydration, or hypoxia. The presentation of painless dark urine strongly suggests gross hematuria or papillary necrosis, requiring immediate clinical evaluation. Option A inappropriately dismisses a potentially serious complication that requires workup. Option B is contraindicated, as aggressive hydration is actually a key component of managing hematuria in these patients. Option D assumes an infectious etiology without supporting evidence, whereas exercise-induced bleeding is a known, specific complication of the trait under physiological stress.

Question 9

The parents of a 2-week-old newborn are distressed after newborn screening results indicate the infant has sickle cell trait. The parents are distressed and ask what treatments their baby needs right now.

  • A) Explain the infant needs lifelong daily prophylactic oral folic acid supplementation.
  • B) Clarify the infant is a healthy carrier and will not develop disease.✓
  • C) Schedule the infant for baseline hemoglobin electrophoresis testing at six months.
  • D) Refer the family to a pediatric hematologist for immediate chronic disease management.

💡 Key Takeaway

Sickle cell trait is a benign carrier state requiring parental reassurance rather than medical intervention.

Show rationale

Newborn screening reliably identifies sickle cell trait, which frequently causes profound parental anxiety due to confusion with the actual disease. The primary nursing action is to provide clear education that the trait is a benign carrier state and the child will not develop sickle cell disease. Options A and D involve interventions and referrals that are standard for managing sickle cell disease, not the trait, and would unnecessarily elevate parental fear. Option C is redundant and unnecessary because the newborn screening has already confirmed the diagnosis using highly sensitive methods like electrophoresis or high-performance liquid chromatography.

Question 10

A 22-year-old female with sickle cell trait asks the nurse practitioner about family planning. She is currently engaged and planning to have children soon.

  • A) Recommend the partner undergo targeted hemoglobin electrophoresis testing before attempting to conceive.✓
  • B) Advise the patient to initiate prophylactic penicillin therapy to ensure a healthy pregnancy.
  • C) Explain that all future children will definitively inherit the sickle cell trait condition.
  • D) Suggest the patient undergo an immediate bone marrow biopsy to assess genetic risk.

💡 Key Takeaway

When one partner has sickle cell trait, testing the other partner is essential for accurate genetic counseling.

Show rationale

When an individual is known to carry the sickle cell trait, the most critical family planning step is testing the partner to determine the risk of having a child with sickle cell disease. If the partner also has the trait, there is a 25% risk of disease for each pregnancy. Option B is incorrect because prophylactic penicillin is a treatment for sickle cell disease, not the trait. Option C is genetically false; inheritance depends entirely on the partner's carrier status. Option D is an invasive, inappropriate procedure that has no role in genetic screening or family planning for hemoglobinopathies.

📄 Want a printable set? 15 high-yield CPN questions + cheat sheet — free PDF

We'll email it now — rationales and key takeaways included, to print or study offline.

Plus 2 short study emails — unsubscribe anytime.

Question 11

An 8-year-old with persistent asthma lives in a basement apartment with wall-to-wall carpeting. The parents report the child has worsening symptoms at night. They wash the child's bedding in hot water weekly. Which intervention should the nurse practitioner recommend next?

  • A) Install a dehumidifier to keep indoor humidity below fifty percent.✓
  • B) Replace the current bedding with synthetic hypoallergenic down comforters.
  • C) Apply acaricide treatments to the bedroom carpeting every three months.
  • D) Keep the bedroom windows open at night to improve air ventilation.

💡 Key Takeaway

Dust mite proliferation is best controlled by maintaining indoor humidity levels below fifty percent.

Show rationale

Basement apartments with carpeting are highly susceptible to high humidity, which promotes dust mite proliferation. While washing bedding in hot water is a great step, dust mites will continue to thrive in the carpet and mattress if the environment remains humid, making humidity below fifty percent the most effective mitigation strategy. Hypoallergenic comforters (B) do not prevent dust mite accumulation if the room is damp. Acaricides (C) are chemical respiratory irritants and are not recommended for asthma management. Opening windows (D) can introduce outdoor moisture and pollen, potentially worsening the child's nighttime symptoms.

Question 12

A 4-year-old child who recently achieved daytime continence begins having frequent accidents and using baby talk during clinic visits. The parent recently separated from a partner following a history of frequent loud altercations. Which assessment finding best differentiates trauma-induced regression from a normative stress response?

  • A) The child exhibits transient clinging behavior during the visit.
  • B) The child displays intense hyperarousal and exaggerated startle.✓
  • C) The child requests a pacifier when feeling tired or hungry.
  • D) The child demonstrates occasional resistance to following rules.

💡 Key Takeaway

Severe autonomic dysregulation differentiates trauma-induced behavioral regression from typical developmental stress responses in preschool children.

Show rationale

While transient clinging and occasional rule resistance can be normative stress responses to family transitions, intense hyperarousal and an exaggerated startle response are specific indicators of trauma exposure. Children exposed to domestic violence often exhibit profound autonomic nervous system dysregulation alongside behavioral regression. Assessing for hyperarousal helps distinguish trauma-induced regression from typical developmental setbacks. Option A is a common, mild stress response. Option C reflects typical self-soothing behavior. Option D is developmentally appropriate limit-testing for a preschooler, lacking the severity of trauma-related dysregulation.

Question 13

A mother brings her 18-month-old toddler, born at 28 weeks gestation, for a well-child visit. The clinic uses the ASQ-3. How should the nurse prepare the screening tool?

  • A) Use the 15-month questionnaire based on corrected age.✓
  • B) Use the 18-month questionnaire based on chronologic age.
  • C) Administer the Denver II instead due to extreme prematurity.
  • D) Delay formal screening until the child reaches 24 months.

💡 Key Takeaway

Prematurity must be corrected for developmental screening until a child reaches 24 months of chronologic age.

Show rationale

When using standardized tools like the ASQ-3 or Denver II, you must calculate the corrected age for any child born before 37 weeks gestation until they reach 24 months of age. Since this child was born at 28 weeks, they are 12 weeks or about 3 months premature. Subtracting 3 months from their 18-month chronologic age gives a corrected age of 15 months, making option A the best choice. Option B is incorrect because using chronologic age would falsely lower the child's scores. Option C is unnecessary as the ASQ-3 is perfectly valid for premature infants when adjusted correctly. Option D is unsafe because early identification of delays is critical, especially for high-risk premature infants.

Question 14

A family caring for a ventilator-dependent 3-year-old is experiencing severe financial hardship and cannot afford out-of-pocket respite care.

  • A) Advise them to apply for a Medicaid Home and Community-Based Waiver.✓
  • B) Suggest they utilize their standard employer-sponsored commercial health insurance plan benefits.
  • C) Recommend they rely exclusively on unpaid community volunteers for nursing care.
  • D) Instruct them to transition the child to a long-term care facility.

💡 Key Takeaway

Medicaid waivers provide crucial financial support for respite care when commercial insurance denies coverage for complex needs.

Show rationale

Families of children with complex medical needs often qualify for Medicaid waivers, which fund in-home nursing and respite services regardless of parental income. Option B is incorrect because commercial insurance rarely covers long-term respite care. Option C is unsafe since a ventilator-dependent child requires skilled nursing. Option D is a drastic last resort, not a primary financial intervention.

Question 15

A 4-year-old child is recovering from an appendectomy and is quietly watching a cartoon. The nurse introduces the Wong-Baker FACES scale to assess pain. The child points to the face depicting "hurts a whole lot" (score 8) despite appearing calm. What is the appropriate nursing response?

  • A) Administer the prescribed analgesic based on the child's self-reported pain score.✓
  • B) Utilize the FLACC behavioral scale to confirm the actual level of pain.
  • C) Ask the child to explain why they chose the crying face picture.
  • D) Document a score of zero because the child appears comfortable and calm.

💡 Key Takeaway

A child's self-report using an age-appropriate scale is the gold standard and overrides behavioral observations.

Show rationale

When a preschooler uses a validated tool like FACES, their self-report is the gold standard for pain assessment. Even if a child appears calm or distracted by a cartoon, nurses must trust and act upon the reported score. Option A is correct because administering the analgesic directly addresses the child's reported pain. Option B is incorrect because behavioral scales like FLACC should not replace self-report when the child is capable of providing one. Option C is inappropriate because it delays care and questions the validity of the child's report without clinical justification. Option D is incorrect because documenting a zero based purely on observation invalidates the child's self-reported score of 8. Distraction is a common coping mechanism in pediatrics and does not mean the child is pain-free.

Question 16

A 9-year-old male presents for a well-child visit. The nurse needs to assess Tanner staging. The child appears anxious and crosses his arms when the nurse approaches. How should the nurse proceed?

  • A) Explain the exam's purpose simply and ask him to untie his gown.✓
  • B) Request the parent leave the room and quickly perform the physical assessment.
  • C) Defer the genital assessment entirely until the child feels much more comfortable.
  • D) Inform the child the provider requires this health check before going home.

💡 Key Takeaway

School-age children require concrete explanations and personal control to manage anxiety regarding bodily exposure.

Show rationale

School-age children require concrete explanations and respect for their developing modesty. Option A addresses both by explaining the clinical reasoning and giving the child control over his own gown, which builds trust. Option B is incorrect because a 9-year-old may still want the parent present, and rushing the exam ignores his visible anxiety. Option C is inappropriate because Tanner staging is a required component of the well-child visit, not something to skip entirely. Option D uses an authoritarian approach that increases anxiety and fails to foster understanding or cooperation.

Question 17

An intubated 2-month-old receiving a continuous midazolam infusion exhibits sudden tachycardia and diaphoresis during routine endotracheal suctioning. Which action is most appropriate?

  • A) Increase the continuous midazolam infusion maintenance rate.
  • B) Apply soft physical restraints to prevent accidental extubation.
  • C) Administer a prescribed rapid-acting intravenous analgesic dose.✓
  • D) Administer a rapid fluid bolus for potential hypovolemia.

💡 Key Takeaway

Sedatives do not provide analgesia; sudden tachycardia and diaphoresis during procedures indicate pain requiring targeted analgesic intervention.

Show rationale

Assessing pain in an intubated, sedated infant requires careful observation of physiologic parameters. Endotracheal suctioning is a highly noxious stimulus. When the infant exhibits sudden tachycardia and diaphoresis during this procedure, these are clear physiologic indicators of acute pain. Option C is the correct action because midazolam is an anxiolytic and sedative, but it completely lacks analgesic properties. Therefore, the infant needs a rapid-acting analgesic to treat the pain. Option A is incorrect because simply increasing the midazolam infusion will deepen sedation without addressing the underlying pain, potentially leading to adverse hemodynamic effects. Option B is incorrect because applying restraints addresses movement but ignores the physiologic distress caused by the painful procedure. Option D is incorrect because the sudden vital sign changes correlate directly with the suctioning procedure, making hypovolemia an unlikely primary cause.

Question 18

The nurse is conducting a HEEADSSS assessment for a 16-year-old female accompanied by her mother. The nurse has completed the Home and Education components. Which action should the nurse take next to continue the assessment?

  • A) Ask the mother to step out of the room to ensure privacy.✓
  • B) Continue the interview while observing the mother's nonverbal reactions very closely.
  • C) Hand the adolescent a standardized screening tool to complete in private.
  • D) Request that the mother remain silent unless the adolescent hesitates significantly.

💡 Key Takeaway

Confidentiality must be established by interviewing the adolescent alone for sensitive HEEADSSS components.

Show rationale

To obtain accurate information during the psychosocial assessment, the nurse must establish confidentiality. While the Home and Education sections can sometimes be discussed with parents present, the subsequent domains (Eating, Activities, Drugs, Sexuality, Suicide, Safety) require privacy. Asking the mother to step out (A) is the standard approach to facilitate open disclosure. Continuing with the mother present (B) or asking her to remain silent (D) inhibits the adolescent's honesty regarding sensitive topics due to fear of parental judgment or discipline. Providing a written tool (C) can supplement the assessment but does not replace the critical therapeutic dialogue and rapport-building required in a comprehensive HEEADSSS interview.

Question 19

During the HEEADSSS assessment, a 17-year-old male reports feeling "down" and admits his grades have dropped significantly over the past three months. He denies current substance use. Which question should the nurse ask next to assess his safety?

  • A) Are you experiencing any bullying or conflicts with peers at your school?
  • B) Have you ever thought about hurting yourself or ending your own life?✓
  • C) Do you think a referral to a school counselor would be helpful?
  • D) Has anyone in your immediate family been diagnosed with a depressive disorder?

💡 Key Takeaway

Direct questioning about suicidal ideation is mandatory when an adolescent exhibits signs of depression.

Show rationale

The "Suicide/Depression" domain of the HEEADSSS assessment requires direct, unambiguous questioning about suicidal ideation when an adolescent displays depressive symptoms, such as feeling down and experiencing academic decline. Option B directly addresses the immediate safety risk. While exploring peer conflicts (A) or family history (D) provides valuable context regarding potential triggers or genetic predispositions, neither takes priority over assessing imminent risk to life. Offering a referral (C) is a premature intervention that skips the critical step of determining the severity of the adolescent's depression and whether emergency psychiatric intervention is required to maintain safety.

Question 20

A nurse is completing the sexuality component of the HEEADSSS assessment for a 15-year-old patient. The patient appears hesitant to discuss dating. Which phrasing is best for the nurse to use to facilitate an open and nonjudgmental conversation?

  • A) Are you currently dating any boys or girls at your high school?
  • B) Are you currently sexually active with anyone, or are you abstaining now?
  • C) Are your romantic attractions primarily toward males, females, or both of them?
  • D) Are you currently involved in a romantic relationship with anyone right now?✓

💡 Key Takeaway

Broad, gender-neutral questions build trust and encourage disclosure during the sexuality assessment.

Show rationale

When initiating the "Sexuality" component of the HEEADSSS assessment, using gender-neutral language and broad, open-ended questions is essential to avoid assumptions and build trust. Option D is inclusive and non-threatening, allowing the adolescent to define their relationships. Option A assumes the patient is limited to dating boys or girls at their school, which may exclude non-binary individuals or partners outside of school. Option B jumps directly to sexual activity, which can be overly intrusive for a hesitant patient who needs a gradual transition into the topic. Option C focuses specifically on the label of attraction rather than the broader, more conversational concept of romantic involvement, which can feel interrogative.

Question 21

A 16-year-old male is being interviewed using the HEEADSSS framework. When asked about substance use, he states, "Most of my friends smoke weed on the weekends, but I don't." Which statement represents the most appropriate follow-up by the nurse?

  • A) It is very important that you continue to avoid using those substances.
  • B) How do you handle situations when your friends offer marijuana to you?
  • C) Have you ever been in a car driven by someone using marijuana?✓
  • D) Do your parents know that your friends are using marijuana on weekends?

💡 Key Takeaway

Assessing indirect risk, such as riding with impaired drivers, is a critical safety component.

Show rationale

The HEEADSSS assessment evaluates both direct and indirect risks. Even if an adolescent denies personal substance use, associating with peers who use drugs introduces significant environmental safety risks. Asking if he has ridden in a car with an impaired driver (C) directly assesses a leading cause of adolescent mortality. Praising his abstinence (A) is supportive but closes the door to further risk assessment. Exploring peer pressure (B) is a valid psychosocial inquiry but is secondary to identifying immediate physical danger like impaired driving. Asking about parental knowledge (D) breaches the collaborative tone of the interview and shifts the focus away from the adolescent's personal safety and decision-making.

Question 22

During a HEEADSSS assessment, a 13-year-old female mentions she recently quit the soccer team and spends most afternoons alone in her bedroom. She denies feeling depressed. Which area should the nurse explore next to understand this behavioral change?

  • A) Ask about her current academic performance and any recent changes in grades.
  • B) Inquire about her online activities, social media use, and potential cyberbullying experiences.✓
  • C) Assess her current dietary habits and any recent intentional weight loss efforts.
  • D) Evaluate her family dynamic and any recent conflicts with her parents recently.

💡 Key Takeaway

Withdrawal from activities often correlates with peer issues or negative online experiences in younger adolescents.

Show rationale

In the "Activities" domain, sudden withdrawal from sports and increased isolation in a 13-year-old are hallmark signs of peer relationship issues or negative online interactions. Exploring social media use and cyberbullying (B) directly addresses common modern stressors that drive adolescents into isolation, even if they deny clinical depression. While academic performance (A), dietary habits (C), and family dynamics (D) are all important components of the comprehensive HEEADSSS assessment, they are less likely to be the primary, immediate driver of sudden peer withdrawal and room isolation compared to the highly influential realm of peer and digital interactions at this specific developmental stage.

Question 23

A 7-year-old child with a suspected influenza infection presents to the clinic. The parent reports giving an over-the-counter liquid for upset stomach over the past two days.

  • A) Advise the parent to discontinue this stomach medication immediately.✓
  • B) Recommend switching to a chewable form of this stomach medication.
  • C) Suggest decreasing this stomach medication dose by half for safety.
  • D) Instruct the parent to administer this stomach medication with food.

💡 Key Takeaway

Bismuth subsalicylate is contraindicated during pediatric viral illnesses due to the risk of Reye syndrome.

Show rationale

Over-the-counter upset stomach remedies frequently contain bismuth subsalicylate. Administering salicylates to children with viral illnesses like influenza or varicella is strictly contraindicated because it dramatically increases the risk of developing Reye syndrome, a life-threatening metabolic encephalopathy. You should advise the parent to stop the medication immediately to mitigate this risk. Recommending a chewable form or decreasing the dose still exposes the child to dangerous salicylates, failing to address the underlying safety threat. Instructing the parent to give the medication with food might help with basic gastrointestinal irritation but completely ignores the severe neurological and hepatic risks associated with salicylate administration during an active viral infection.

Question 24

A 15-year-old adolescent taking prescribed daily sertraline for depression reports starting a herbal supplement for mood enhancement purchased at a health food store.

  • A) Assess this adolescent for signs of increased bleeding tendencies.
  • B) Evaluate this adolescent for symptoms of excessive neuromuscular activity.✓
  • C) Monitor this adolescent for episodes of sudden severe hypotension.
  • D) Examine this adolescent for evidence of acute hepatic impairment.

💡 Key Takeaway

Combining SSRIs with St. John's wort increases the risk of life-threatening serotonin syndrome.

Show rationale

The most common over-the-counter herbal supplement used for mood enhancement is St. John's wort. When taken concurrently with selective serotonin reuptake inhibitors like sertraline, it can precipitate serotonin syndrome due to an excessive accumulation of serotonin. You need to evaluate the patient for hallmark symptoms such as excessive neuromuscular activity, which includes hyperreflexia, clonus, and tremors. Assessing for bleeding tendencies is more appropriate for supplements like ginkgo biloba or garlic. Monitoring for sudden severe hypotension is incorrect, as serotonin syndrome typically presents with autonomic instability leaning toward hypertension and tachycardia. Examining for acute hepatic impairment is not the immediate priority, as liver toxicity is not the primary acute interaction between SSRIs and this specific herbal supplement.

Question 25

A 10-year-old child with attention-deficit/hyperactivity disorder experiences sleep latency issues. The parent reports administering an over-the-counter melatonin gummy immediately before the child gets into bed.

  • A) Advise giving the supplement thirty to sixty minutes before bedtime.✓
  • B) Recommend increasing the supplement dose if sleep is not achieved.
  • C) Suggest replacing the supplement with a prescribed sedative hypnotic agent.
  • D) Instruct stopping the supplement due to severe stimulant medication interactions.

💡 Key Takeaway

Melatonin should be administered 30 to 60 minutes before bedtime to effectively reduce sleep latency.

Show rationale

Melatonin is frequently utilized to manage sleep onset delay in children with ADHD, particularly those taking stimulant medications. However, for melatonin to be effective, it must be timed to align with the body's natural circadian rhythm. You should advise the parent to administer the supplement 30 to 60 minutes prior to the desired bedtime rather than right as the child gets into bed. Recommending a dose increase without first correcting the administration timing is inappropriate and could lead to daytime grogginess. Suggesting a switch to a prescribed sedative hypnotic is an unnecessary escalation for a common issue that often resolves with proper sleep hygiene and melatonin timing. Instructing them to stop the supplement due to severe interactions is incorrect, as melatonin is generally safe to use alongside ADHD stimulants.

Question 26

A 14-year-old female with iron deficiency anemia reports taking her prescribed ferrous sulfate alongside an over-the-counter calcium carbonate antacid to prevent stomach upset.

  • A) Praise the adolescent for proactively managing gastrointestinal medication side effects.
  • B) Suggest switching the antacid to a bismuth-based over-the-counter liquid suspension.
  • C) Explain that the antacid will significantly decrease the iron absorption.✓
  • D) Recommend taking both medications with a large glass of whole milk.

💡 Key Takeaway

Calcium carbonate binds with iron in the gastrointestinal tract, significantly reducing its therapeutic absorption.

Show rationale

When calcium carbonate antacids are taken concurrently with iron supplements, the calcium binds to the iron in the gastrointestinal tract, forming an insoluble complex. This interaction significantly decreases iron absorption, rendering the prescribed ferrous sulfate ineffective for treating her anemia. You should explain this interaction and advise separating the doses by at least two hours. Praising the adolescent is incorrect because, while her intention is good, her action directly undermines her anemia treatment. Suggesting a switch to a bismuth-based suspension is inappropriate as it can also interfere with absorption and introduces unnecessary salicylates. Recommending taking both with a large glass of whole milk is counterproductive, as the high calcium content in the milk will further inhibit the absorption of the iron supplement.

Question 27

When assessing a 3-year-old male with recurrent pseudomonas pneumonias, the nurse notes the parents are healthy first cousins. How should the nurse accurately map this relationship on the family pedigree?

  • A) Draw a double horizontal line between the parents.✓
  • B) Draw a single vertical line between the parents.
  • C) Draw a dashed diagonal line across the parents.
  • D) Draw a dotted horizontal line between the parents.

💡 Key Takeaway

Consanguineous relationships are mapped on a pedigree using a double horizontal line between the partners.

Show rationale

The child's presentation suggests cystic fibrosis, an autosomal recessive condition. The parents being first cousins indicates consanguinity, which significantly increases the risk for autosomal recessive disorders. In standard pedigree nomenclature, a double horizontal line between male and female symbols denotes a consanguineous mating. Option B is incorrect because a vertical line connects parents to offspring. Option C is incorrect as a diagonal line indicates a deceased individual. Option D is incorrect because a dashed or dotted line typically represents a casual relationship or adoption, not a biological consanguineous union.

Question 28

A male infant with severe bleeding after circumcision has two maternal uncles with similar bleeding and an unaffected father. How should the nurse map the suspected genetic transmission for this family?

  • A) Mark the father as a carrier using a half-shaded square.
  • B) Mark the mother as a carrier using a half-shaded circle.✓
  • C) Mark the infant as unaffected using a fully shaded square.
  • D) Mark the uncle as a carrier using a half-shaded square.

💡 Key Takeaway

X-linked recessive conditions are passed from carrier mothers to affected sons, mapped with half-shaded circles.

Show rationale

The presentation of a bleeding disorder in a male infant and maternal uncles, with an unaffected father, strongly suggests an X-linked recessive condition like hemophilia. In this inheritance pattern, females are typically asymptomatic carriers who pass the mutated gene to their sons. Therefore, the mother is an obligate carrier, correctly mapped using a half-shaded circle. Option A is incorrect because the father is unaffected and cannot be a carrier of an X-linked trait. Option C is incorrect as the infant is affected, requiring a fully shaded square. Option D is incorrect because the uncles are affected, not carriers, and would be fully shaded squares.

Question 29

A nurse evaluates the initial patient seeking genetic evaluation who presents with six café-au-lait spots and notes the paternal grandmother has similar lesions. How should the nurse designate this specific patient on the pedigree?

  • A) Indicate the father with a bracket placed around the symbol.
  • B) Indicate the grandmother with a bracket placed around the symbol.
  • C) Indicate the child with an arrow pointing to the symbol.✓
  • D) Indicate the father with an arrow pointing to the symbol.

💡 Key Takeaway

The proband is the initial patient seeking genetic evaluation and is designated by an arrow.

Show rationale

The patient presenting with café-au-lait spots is the proband, which is the first affected family member who brings the family to medical attention for genetic evaluation. Standard pedigree nomenclature dictates that the proband is identified by an arrow pointing to their symbol. Options A and B are incorrect because brackets are typically used to denote adopted individuals, not the proband. Option D is incorrect because although the grandmother has similar lesions suggesting an autosomal dominant pattern like neurofibromatosis, the child is the initial patient seeking evaluation and thus serves as the proband.

Question 30

A nurse is preparing to administer an intramuscular injection to a 7-year-old child who has severe atopic dermatitis with excoriated skin on both extremities. How should the nurse proceed with pain mitigation?

  • A) Apply the vibrating cold device directly over the excoriated skin.
  • B) Use a vapocoolant spray directly on the compromised skin area.
  • C) Place the vibrating cold device proximally on intact skin tissue.✓
  • D) Administer the injection without utilizing any topical pain mitigation.

💡 Key Takeaway

Pain mitigation devices can be placed on proximal intact skin when the injection site area is compromised.

Show rationale

When using a vibrating cold device, it is crucial to avoid placing the frozen ice pack or vibrating unit directly over broken, irritated, or excoriated skin to prevent further tissue damage and infection. However, the nurse can still utilize the Gate Control Theory by placing the device proximally on healthy, intact skin to intercept the pain signals. Option A is incorrect because applying the device over excoriated skin can exacerbate the dermatitis and cause severe discomfort. Option B is incorrect because vapocoolant sprays contain propellants that will burn and irritate compromised skin. Option D is incorrect because the nurse should always attempt to provide appropriate pain management, and alternative placements allow for effective mitigation without compromising the child's skin integrity.

Question 31

A 16-year-old with a history of depression is preparing for discharge, and the nurse is creating a discharge safety plan.

  • A) Instruct the parents to remove all potentially dangerous items from the home.
  • B) Provide a standardized safety contract for the teen and parents to sign.
  • C) Guide the teen to identify personal warning signs and preferred support contacts.✓
  • D) Remind the teen to call the emergency hotline if symptoms suddenly worsen.

💡 Key Takeaway

Collaborative safety planning that respects the adolescent's input is more effective than standardized or parent-directed interventions.

Show rationale

Guiding the adolescent to identify their own warning signs and preferred contacts respects their input and ensures the safety plan is personalized and realistic. This collaborative approach increases the likelihood that the teen will actually use the plan. Option A is incorrect because focusing exclusively on the parents removes the teen from the process, failing to build their self-regulation skills. Option B is incorrect because a standardized contract does not reflect the adolescent's unique triggers or coping strategies, making it less effective than a personalized plan. Option D is incorrect because simply reminding the teen to call a hotline is a directive approach that lacks the comprehensive, collaborative planning needed for effective mental health support. Engaging teens directly is vital.

Question 32

A 4-month-old infant who is exclusively breastfed presents to the clinic with poor weight gain over the last month despite regular pancreatic enzyme administration. Which dietary adjustment is most appropriate?

  • A) Switch the infant completely to a standard formula.
  • B) Fortify expressed breast milk with high-calorie formula powder.✓
  • C) Introduce solid foods like rice cereal to feedings.
  • D) Restrict feeding times to increase the infant's hunger.

💡 Key Takeaway

Infants with cystic fibrosis often require fortified breast milk to meet their high caloric demands.

Show rationale

Infants with CF often struggle with poor weight gain due to malabsorption and increased metabolic demand. The best approach is to increase the caloric density of their intake by fortifying breast milk with high-calorie formula powder, which preserves the immunological benefits of breast milk while providing necessary calories. Switching entirely to standard formula (Option A) removes breast milk benefits and may still lack sufficient calories for a CF patient. Introducing solids at four months (Option C) is developmentally inappropriate and lacks dense calories. Restricting feeds (Option D) will only worsen the poor weight gain.

Question 33

While assessing a 10-year-old with a spontaneous pneumothorax, the nurse practitioner notes intermittent bubbling in the water seal chamber during exhalation. The fluid level shows expected tidaling with respirations. What is the most appropriate action?

  • A) Clamp the chest tube close to the insertion site.
  • B) Document the findings as an expected clinical resolution.✓
  • C) Prepare for immediate chest tube removal by the provider.
  • D) Check the entire drainage system for a loose connection.

💡 Key Takeaway

Intermittent bubbling in the water seal during exhalation is expected while a pneumothorax is resolving.

Show rationale

When managing a pneumothorax, intermittent bubbling in the water seal chamber during exhalation or coughing is a normal finding that indicates air is successfully leaving the pleural space. Because this is an expected part of the healing process, you should simply document the findings. Continuous bubbling would indicate an air leak in the system, which would require checking connections. Clamping the chest tube is dangerous and could cause a tension pneumothorax. While the presence of tidaling and intermittent bubbling shows the system is working, it also means the pneumothorax has not completely resolved yet, so preparing for immediate removal is premature.

Question 34

A 5-year-old requires a central line dressing change, and the nurse wants to use therapeutic play rather than procedural preparation to reduce anxiety. Which activity is most appropriate?

  • A) Having the child place a sterile dressing on a favorite doll.
  • B) Showing the child the exact supplies used for the dressing change.
  • C) Letting the child use medical tape and gauze to create artwork.✓
  • D) Explaining each step of the dressing change using simple, concrete terms.

💡 Key Takeaway

Therapeutic play uses medical items for creative expression rather than direct procedural instruction.

Show rationale

Letting the child create artwork with tape and gauze is a form of undirected therapeutic play that helps reduce anxiety by making medical supplies familiar and non-threatening without the pressure of an impending procedure. Option A is a form of medical play used specifically for procedural preparation, as it mimics the exact clinical event the child is about to experience. Option B is also a direct preparatory technique rather than an expressive play activity. Option D is a cognitive preparation strategy that provides necessary information but lacks the active, play-based engagement required to meet the definition of therapeutic play for a preschool-aged child facing a stressful central line dressing change.

Question 35

A 10-year-old child with relapsed acute lymphoblastic leukemia is admitted for palliative care. The parents ask the nurse practitioner if a new clinical trial will cure their child. What is the most appropriate response?

  • A) I see you are hoping for a cure, but we must focus on comfort.
  • B) Please tell me what the oncology team has shared with you about this trial.✓
  • C) Clinical trials are experimental and rarely provide a cure for relapsed acute lymphoblastic leukemia.
  • D) We should schedule a formal family meeting with the oncologist to discuss trial details.

💡 Key Takeaway

Always assess a family's baseline understanding before delivering complex or difficult prognostic information.

Show rationale

When discussing a poor prognosis or addressing unrealistic expectations in a palliative setting, the first step is to assess the family's current understanding. Using the SPIKES protocol, this aligns with assessing perception. Option B correctly invites the parents to share what they already know, providing a baseline for honest and compassionate communication. Option A dismisses the parents' inquiry prematurely without exploring their understanding, which can damage rapport. Option C delivers blunt medical information without first assessing readiness or prior knowledge, which can be overwhelming and perceived as insensitive. Option D defers the conversation entirely; while a family meeting may be necessary later, the immediate need is to explore the parents' current thoughts and feelings to guide the next steps in the prognostic discussion.

Question 36

The parents of a 9-year-old boy with Duchenne muscular dystrophy who experiences frequent falls during ambulation ask about starting a physical therapy routine. Which activity should the nurse practitioner recommend?

  • A) Encourage daily high resistance weight training exercises.
  • B) Recommend eccentric lower extremity muscle strengthening routines.
  • C) Prescribe submaximal aerobic aquatic swimming therapy sessions.✓
  • D) Advise strict physical rest to conserve muscle energy.

💡 Key Takeaway

Submaximal aerobic exercise like swimming maintains conditioning in muscular dystrophy without causing contraction-induced muscle damage.

Show rationale

For a child with Duchenne muscular dystrophy who is still ambulatory but experiencing falls, submaximal aerobic exercise such as swimming is highly recommended. Aquatic therapy provides buoyancy, reducing fall risk while maintaining cardiovascular health and muscle tone without overexertion. High-resistance weight training and eccentric muscle strengthening (like downhill walking or heavy weightlifting) are strictly contraindicated because they cause contraction-induced muscle fiber damage that the dystrophin-deficient muscle cannot repair, accelerating disease progression. Conversely, advising strict physical rest is detrimental, as it leads to rapid deconditioning, weight gain, and the early development of joint contractures. The goal is to balance safe, low-impact mobility with energy conservation.

Question 37

While assisting with a lumbar puncture on a 3-month-old infant held in a lateral decubitus position, the nurse notes the infant's oxygen saturation drops to 86%. Which action should the nurse take?

  • A) Extend the infant's neck slightly to open the airway.✓
  • B) Administer supplemental oxygen via a non-rebreather mask immediately.
  • C) Reposition the infant into a seated, forward-leaning posture.
  • D) Alert the provider to withdraw the spinal needle immediately.

💡 Key Takeaway

Extreme neck flexion during infant lumbar punctures can cause mechanical airway obstruction requiring slight extension.

Show rationale

In infants, extreme neck flexion during lateral decubitus positioning for a lumbar puncture can compress the trachea and cause airway obstruction. Extending the neck slightly relieves this mechanical compression without abandoning the procedure. Option B treats the symptom of hypoxia but ignores the mechanical cause of the airway compromise. Option C is inappropriate mid-procedure and provides a less secure hold for a young infant. Option D is premature because the nurse should first attempt to open the airway through simple repositioning before stopping the procedure entirely.

Question 38

A lethargic 4-year-old undergoes a lumbar puncture. The preliminary fluid analysis reveals a CSF glucose of 25 mg/dL and a neutrophil predominance. Which intervention should the nurse anticipate?

  • A) Monitor the child closely while awaiting viral culture results.
  • B) Prepare to administer prescribed intravenous broad-spectrum antibiotic therapy.✓
  • C) Initiate intravenous acyclovir therapy for suspected viral encephalitis.
  • D) Prepare for a repeat lumbar puncture to confirm findings.

💡 Key Takeaway

Cerebrospinal fluid with low glucose and high neutrophils indicates bacterial meningitis requiring immediate antibiotics.

Show rationale

A CSF glucose of 25 mg/dL combined with neutrophil predominance strongly indicates bacterial meningitis, which is a medical emergency requiring immediate antibiotics. Option A is incorrect because the fluid profile points to a bacterial rather than a viral etiology, so waiting is dangerous. Option C is incorrect because acyclovir treats herpes encephalitis, which typically presents with a lymphocytic pleocytosis and a normal glucose level. Option D is unnecessary and would inappropriately delay critical life-saving treatment for this highly vulnerable patient.

Question 39

The provider is preparing to perform a lumbar puncture on a cooperative 14-year-old with a high BMI. Which positioning strategy should the nurse use to best maximize the interspinous spaces?

  • A) Place the patient in a prone position with pillows.
  • B) Position the patient in a tight lateral decubitus curl.
  • C) Maintain the patient in a supine position during prep.
  • D) Have the patient sit on the bed leaning forward.✓

💡 Key Takeaway

The seated forward-leaning position maximizes interspinous spaces for lumbar punctures in cooperative older children.

Show rationale

For a cooperative 14-year-old with a high BMI, the seated and forward-leaning position uses gravity to help maximize the interspinous spaces and makes midline identification much easier for the provider. Option A and Option C do not open the vertebral spaces effectively for needle insertion and are not standard positions for this procedure. Option B is a valid position that is frequently used for infants or uncooperative children, but the seated position is often preferred in older and cooperative adolescents with higher body mass to better palpate the necessary landmarks.

Question 40

An adolescent reports a throbbing headache that worsens when sitting upright approximately 24 hours after a lumbar puncture. Which action should the nurse take to manage this symptom?

  • A) Encourage the adolescent to remain in a supine position.✓
  • B) Elevate the head of the bed to forty-five degrees.
  • C) Administer a prescribed prophylactic broad-spectrum intravenous antibiotic immediately.
  • D) Prepare the adolescent for an emergent computed tomography scan.

💡 Key Takeaway

Post-dural puncture headaches worsen when upright and are initially managed by maintaining a supine position.

Show rationale

A headache that worsens when sitting upright shortly after a lumbar puncture is a classic post-dural puncture headache caused by cerebrospinal fluid leakage. Remaining supine helps equalize pressure and usually relieves the symptoms. Option B would likely exacerbate the headache by increasing the pressure gradient and promoting further fluid leakage. Option C is incorrect as there are no described signs of infection like fever or altered mental status to justify antibiotics. Option D is an overreaction to a common and benign complication that initially requires conservative postural management.

Question 41

A 3-day-old term infant born at 39 weeks gestation has a positive newborn screen for cystic fibrosis. The infant currently weighs 1.8 kg and is receiving parenteral nutrition. The PNP is planning the diagnostic workup.

  • A) Schedule the sweat chloride test for tomorrow morning.
  • B) Delay the sweat test until weight exceeds two kilograms.✓
  • C) Order immediate CFTR genetic sequencing from a blood sample.
  • D) Perform a fecal elastase test to confirm the diagnosis.

💡 Key Takeaway

Infants must weigh at least 2 kg and be 48 hours old for valid sweat chloride testing.

Show rationale

The sweat chloride test is the gold standard for CF diagnosis but requires the infant to be at least 48 hours old and weigh more than 2 kg to avoid a quantity not sufficient result. Because this infant weighs 1.8 kg, testing must be delayed. Scheduling it for tomorrow is incorrect due to the weight restriction. Ordering immediate genetic sequencing is not the first-line diagnostic step for a positive newborn screen before a sweat test. Fecal elastase evaluates pancreatic insufficiency and does not replace the primary diagnostic test.

Question 42

A 4-month-old infant with poor weight gain undergoes a sweat chloride test. The laboratory reports a sweat chloride level of 45 mmol/L with adequate sweat volume collected.

  • A) Reassure the parents that this result rules out cystic fibrosis.
  • B) Diagnose cystic fibrosis and initiate pancreatic enzyme replacement therapy immediately.
  • C) Repeat the sweat chloride test and order CFTR genetic analysis.✓
  • D) Schedule a pulmonary function test to assess for airway obstruction.

💡 Key Takeaway

A sweat chloride level between 30 and 59 mmol/L is indeterminate and requires further genetic testing.

Show rationale

A sweat chloride level between 30 and 59 mmol/L is considered intermediate or indeterminate for cystic fibrosis across all age groups. The appropriate management is to repeat the sweat test and perform CFTR genetic testing to clarify the diagnosis. Reassuring the parents is incorrect because an intermediate result does not rule out the disease. Diagnosing CF and starting enzymes is premature because a level of 60 mmol/L or higher is required for a definitive diagnosis. Pulmonary function tests are not developmentally appropriate or diagnostic for a 4-month-old infant.

Question 43

The nurse practitioner is preparing a 2-year-old toddler with recurrent pneumonia for an outpatient sweat chloride test. The parents ask how they should prepare the child the morning of the procedure.

  • A) Withhold all oral fluids for four hours before the test.
  • B) Apply a thick moisturizing lotion to both arms and legs.
  • C) Administer a prophylactic dose of oral antibiotics before the visit.
  • D) Ensure the child is well hydrated and eats normal meals.✓

💡 Key Takeaway

Adequate hydration and avoiding topical creams are essential preparations for an accurate sweat chloride test.

Show rationale

Proper preparation for a sweat chloride test requires the child to be well hydrated to ensure an adequate sweat yield. Fasting or withholding fluids is contraindicated because dehydration increases the risk of a quantity not sufficient result. Applying lotions or creams to the arms and legs is incorrect because it can interfere with the pilocarpine iontophoresis process and alter the test results. Administering prophylactic antibiotics is unnecessary for this noninvasive diagnostic test. Therefore, maintaining normal feeding and hydration is the only correct preparation.

Question 44

A 6-week-old infant with severe atopic dermatitis covering both arms and legs undergoes a sweat chloride test. The laboratory reports a sweat volume of 40 mg.

  • A) Recognize the sample is insufficient and schedule a repeat test.✓
  • B) Interpret this low volume as a negative screen for CF.
  • C) Send the collected sample for immediate CFTR genetic mutation analysis.
  • D) Diagnose cystic fibrosis based on the reduced sweat gland function.

💡 Key Takeaway

A minimum sweat volume of 75 mg is required to ensure the validity of the test results.

Show rationale

A valid sweat chloride test requires a minimum sweat volume, typically 75 mg for the Gibson-Cooke method, to ensure accuracy. A volume of 40 mg is a quantity not sufficient result, which is more common in young infants or those with skin conditions like severe eczema. This requires scheduling a repeat test once the skin clears or using an alternative site. Interpreting this as negative or diagnostic is incorrect because the sample is invalid. The collected sweat cannot be used for genetic mutation analysis, which requires blood or a buccal swab.

Question 45

A 12-month-old child presents with severe malnutrition and generalized pitting edema. The provider notes a sweat chloride test performed yesterday returned a result of 22 mmol/L.

  • A) Accept the result as a definitive exclusion of cystic fibrosis.
  • B) Order an immediate sweat test using the child's lower extremities.
  • C) Repeat the sweat test after the child's nutritional status improves.✓
  • D) Initiate pancreatic enzyme therapy despite the normal sweat chloride level.

💡 Key Takeaway

Severe edema and malnutrition can cause false-negative sweat chloride results due to electrolyte dilution.

Show rationale

A sweat chloride level below 29 mmol/L is generally considered normal. However, severe malnutrition and generalized edema can cause false-negative results due to the dilution of electrolytes in the sweat. The test should be repeated once the child's nutritional status and edema have resolved to ensure an accurate reading. Accepting the result is incorrect because the clinical presentation strongly suggests a high risk for a false negative. Repeating the test immediately on the lower extremities will not resolve the systemic dilution issue. Starting enzymes without a confirmed diagnosis is outside standard practice guidelines.

Question 46

A 2-day-old neonate is admitted after a failed critical congenital heart disease screen. An urgent echocardiogram confirms severe coarctation of the aorta. Which intervention should the nurse plan to implement?

  • A) Initiate a continuous intravenous alprostadil infusion.✓
  • B) Administer a rapid isotonic fluid bolus.
  • C) Prepare the infant for immediate surgery.
  • D) Begin a continuous intravenous furosemide infusion.

💡 Key Takeaway

Alprostadil is essential to maintain ductal patency and systemic perfusion in ductal-dependent congenital heart lesions.

Show rationale

For a neonate with severe coarctation, systemic blood flow depends heavily on a patent ductus arteriosus. Initiating an alprostadil infusion is the critical first step to maintain ductal patency and ensure adequate systemic perfusion. Administering a fluid bolus (Option B) might worsen pulmonary congestion if left-sided heart pressures are already elevated. Preparing for immediate surgery (Option C) is not the immediate priority; the infant must first be hemodynamically stabilized with prostaglandins before surgical planning occurs. Furosemide (Option D) is contraindicated at this moment because it can deplete intravascular volume, which would further compromise systemic perfusion in a ductal-dependent state.

Question 47

A 10-month-old infant with extensive burns requires a daily debridement. The provider orders intravenous fentanyl to be administered exactly during the dressing change. The nurse recognizes this timing will cause unnecessary suffering. How should the nurse advocate for this infant?

  • A) Request to change the medication to oral morphine.
  • B) Suggest adding a topical anesthetic to the dressing.
  • C) Advocate to administer the dose prior to starting.✓
  • D) Ask to switch the fentanyl to intravenous ketorolac.

💡 Key Takeaway

Procedural analgesia must be timed so the medication reaches its peak effect before the painful stimulus begins.

Show rationale

Procedural pain management requires medications to reach their peak effect before the painful stimulus begins. Intravenous fentanyl acts quickly but still requires a few minutes to reach peak efficacy. Option C is correct because advocating for pre-procedural administration ensures the infant is comfortable when the painful debridement actually starts. Option A is incorrect because oral morphine takes too long to peak for an immediate procedure. Option B is insufficient for the severe, deep pain of burn debridement. Option D steps down the analgesia inappropriately, as ketorolac will not cover severe burn pain.

Question 48

A 16-year-old receiving palliative care for metastatic osteosarcoma reports constant 9/10 bone pain. The provider is reluctant to increase the scheduled methadone dose, because the provider cites concerns about potential addiction. How should the nurse respond to this provider?

  • A) Clarify that tolerance is expected and requires titration.✓
  • B) Suggest alternating the methadone with a weak opioid.
  • C) Recommend utilizing cognitive behavioral therapy for the pain.
  • D) Propose weaning the methadone to prevent physical dependence.

💡 Key Takeaway

In palliative care, expected pharmacological tolerance must be differentiated from addiction to ensure aggressive and appropriate pain management.

Show rationale

In pediatric palliative care, the primary goal is optimal symptom management. Providers sometimes confuse physical dependence and pharmacological tolerance with psychological addiction, leading to severe under-dosing. Option A is correct because educating the provider that tolerance is an expected physiological response justifies the need for dose titration to achieve comfort. Option B is inappropriate because alternating with a weak opioid will not manage severe, escalating cancer pain. Option C is a useful non-pharmacological adjunct but does not replace necessary opioid titration. Option D is harmful, as weaning will cause withdrawal and severely exacerbate the patient's suffering.

Question 49

A family is seeking a second opinion for their 12-year-old with refractory epilepsy. They ask the nurse what they should do about the currently prescribed antiepileptic medications while waiting for the appointment. Which guidance should the nurse provide?

  • A) Instruct them to taper the medications slowly so the new neurologist can assess baseline activity.
  • B) Tell them to stop the medications immediately since they feel the current treatment is ineffective.
  • C) Suggest they reduce the dosage by half until the second opinion appointment is officially scheduled.
  • D) Advise them to continue the current medication regimen to prevent breakthrough seizures during the transition.✓

💡 Key Takeaway

Maintaining patient safety and continuity of care is essential while families await a second medical opinion.

Show rationale

While supporting a second opinion, the nurse must ensure patient safety and continuity of care. Stopping or altering antiepileptics without a provider's order risks status epilepticus and severe harm. Option D maintains safety and continuity of care. Options A, B, and C involve the nurse inappropriately prescribing or altering medical therapies, which falls outside the nursing scope of practice and directly endangers the patient.

Question 50

After receiving a second opinion for a 15-year-old with Crohn's disease, the family is confused because the two treatment plans differ significantly. They ask the nurse which provider they should trust. Which action is best?

  • A) Recommend they follow the original provider's plan to maintain continuity of their current care.
  • B) Suggest they choose the second provider's plan since it represents a newer clinical perspective.
  • C) Facilitate a care conference with the family and providers to discuss the differing approaches.✓
  • D) Advise them to seek a third opinion to determine which of the plans is most appropriate.

💡 Key Takeaway

When treatment plans conflict, nurses should facilitate collaborative communication to support shared decision-making.

Show rationale

When families face conflicting medical advice, the nurse's role is to facilitate communication and support the family's decision-making process. A care conference allows open dialogue about the risks, benefits, and rationale of each plan. Options A and B inappropriately direct the family's choice, which violates their autonomy and oversteps the nursing role. Option D adds unnecessary delay, stress, and expense without resolving the current confusion, undermining shared decision-making.

Practice CPN by topic

30 topics covered — each with real questions, rationales, and key takeaways.

Free CPN cheat sheets

Printable quick-reference guides — study them right here or download the PDF.

2,200+

questions in the app

30

topics covered

10+ yrs

exam-prep publishing

Free

on iOS & Android

Built to help you pass faster — by exam-prep publishers with 10+ years' experience and 150,000+ books sold

  • 💡 Key Takeaways — the one transferable rule per question
  • 🔍 Hint highlights — the decisive cue phrases in each stem
  • 📖 Full rationales — why every option is right or wrong

Every CPN question is written to the current exam outline for quick learning and a clear pass strategy.

CPN® is a registered mark of the Pediatric Nursing Certification Board (PNCB). PNCB does not sponsor or endorse LexPort.

📱 CPN Pediatric Nurse Exam 2026 — by LexPort

2,200+ CPN questions — free in the app

You've seen a sample. Get the complete experience — a timed exam simulator, every rationale, and progress tracking that shows exactly what to study next.

This page shows a few free samples. The app has all 2,200+ CPN questions, a timed mock exam, and offline study.

★★★★★5.0 · 8 App Store ratings
  • Written to the current PNCB exam outline
  • 10+ years publishing exam-prep books · 150,000+ books sold
  • ✓ Timed exam simulator — real conditions
  • ✓ Every answer explained + key takeaway
  • ✓ Tracks your weak topics
  • ✓ Works offline · Free to start
CPN · Exam Simulator

The parents of a 2-week-old newborn are distressed after newborn screening results indicate the infant has sic…

A) Explain the infant needs lifelong daily
B) Clarify the infant is a healthy carrier
C) Schedule the infant for baseline hemoglo
D) Refer the family to a pediatric hematolo
Submit Answer

📄 Free: 15 high-yield CPN questions + cheat sheet (PDF)

Enter your email and we'll send the printable PDF — rationales and key takeaways included.

Plus 2 short study emails — unsubscribe anytime.

CPN questions & answers

Compare & decide

Authoritative sources