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Palliative & End-of-Life Care for the CMSRN Exam

End-of-life topics appear across multiple domains, including Holistic Patient Care, which makes up 15% of your 125 scored items. You must know how to manage refractory symptoms, navigate advance directives, and handle post-mortem regulatory guidelines. Test your readiness with our CMSRN practice test covering these specific clinical scenarios.

Written and reviewed by the LexPort exam-prep team, led by our Founder & Exam-Prep Lead. LexPort builds certification practice questions โ€” this is exam-preparation material, not medical advice. Last reviewed June 2026.

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Question 1 of 5โ˜… 0/5

An 82-year-old with advanced dementia hospitalized for dehydration has a valid DPOA-HC designating a niece as agent. The niece requests a feeding tube, but the patient's living will states "no artificial nutrition." The care team notes the niece recently gained inheritance rights. How should the nurse proceed?

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Test yourself: Palliative & End-of-Life Care

Three CMSRN practice questions on palliative & end-of-life care โ€” tap an answer for instant feedback. The app has 5,200+, timed and scored.

Question 1

A veteran with PTSD loses his wife unexpectedly. At his 8-week follow-up, he reports hypervigilance and avoiding her belongings. He states, "I feel numb but rage at night." Which resource aligns with trauma-informed bereavement care?

โ–ธ Why A is the answer

Trauma symptoms (hypervigilance, rage, avoidance) with preexisting PTSD require specialized care. Option A integrates military context and trauma expertise. Option B lacks PTSD accommodation. Option C medicates symptoms without addressing grief. Option D may retraumatize through exposure. AMSN standards emphasize specialized pathways for traumatic loss with comorbidities.

Question 2

A hospice patient from Ghana expresses fear of ancestors' displeasure if burial traditions aren't followed. The daughter mentions specific cloth-wrapping rituals. Which nursing documentation is essential?

โ–ธ Why C is the answer

Option C addresses both spiritual (ancestor traditions) and collateral (daughter's details) cues by ensuring actionable preservation of rituals. AMSN standards require documenting concrete cultural practices for continuity. Option A notes symptoms without solutions. Option B inaccurately places ritual details in legal paperwork. Option D prioritizes bureaucracy over patient values. The HPNA guidelines emphasize translating spiritual concerns into measurable care plans to honor cultural identity at death.

Question 3

A daughter caring for her father with advanced dementia reports missing work due to his wandering episodes. The patient has Medicaid and lives in a rural area. Which respite option best balances safety, accessibility, and coverage?

โ–ธ Why B is the answer

Medicaid waiver programs cover in-home respite in rural areas, addressing wandering safety during work hours without relocation. Option A is less feasible due to limited hospital-based programs in rural settings. Option C exceeds typical Medicaid respite duration (usually โ‰ค5 days). Option D creates financial strain, contradicting caregiver support principles. The Family Caregiver Alliance recommends home-based respite for dementia to minimize disorientation, with Medicaid waivers specifically designed for low-income families in underserved areas.

Question 1

An 82-year-old with advanced dementia hospitalized for dehydration has a valid DPOA-HC designating a niece as agent. The niece requests a feeding tube, but the patient's living will states "no artificial nutrition." The care team notes the niece recently gained inheritance rights. How should the nurse proceed?

  • A) A) Advocate for the niece's decision since she holds legal authority as DPOA-HC.
  • B) B) Refuse the feeding tube based on the living will's explicit instructions.
  • C) C) Clarify the niece's rationale and report concerns of potential conflict of interest.โœ“
  • D) D) Defer to the physician's judgment regarding clinical appropriateness of the tube.
Show rationale

While DPOA-HC agents must follow known patient wishes, the niece's inheritance and contradictory request raise red flags. The nurse must investigate inconsistencies per ethical obligations (B is incorrect without due process). Reporting safeguards against undue influence without usurping legal authority (A ignores the conflict). Clinical decisions (D) are secondary to establishing valid consent. The nurse should collaborate with ethics/social work to ensure the agent acts in the patientโ€™s best interests.

Question 2

A conscious patient with pleural mesothelioma has refractory dyspnea despite maximal opioids. Chest X-ray shows large right pleural effusion. The patient declines thoracentesis due to prior discomfort. Which alternative intervention is indicated?

  • A) A) Administer high-dose corticosteroids orally
  • B) B) Apply cold compresses to the patient's chest
  • C) C) Initiate therapeutic indwelling pleural catheterโœ“
  • D) D) Provide handheld fan with directed airflow
Show rationale

Indwelling catheters allow repeated drainage with minimal discomfort, aligning with patient's refusal of thoracentesis and effusion evidence. Steroids (A) lack evidence for malignant effusions and cause side effects. Cold compresses (B) have no proven dyspnea benefit. Fans (D) provide minimal relief for mechanical compression. Catheter placement directly addresses the physiological barrier (effusion) while respecting autonomy through a less invasive option.

Question 3

After pronouncing death, a nurse discovers the deceased has an implanted radioactive seed for prostate cancer. Which action follows regulatory guidelines?

  • A) A) Placing a radiation warning tag on the body bag before morgue transferโœ“
  • B) B) Notifying nuclear medicine to retrieve the device prior to funeral home release
  • C) C) Documenting the implant only in the nursing notes for coroner review
  • D) D) Asking family to sign a radiation exposure waiver for visitation
Show rationale

NRC regulations require radiation hazard labeling for bodies with radioactive implants. Option A ensures safe handling. Option B is incorrect; seeds aren't retrieved as they pose minimal risk. Option C is insufficient; hazard documentation must accompany the body. Option D is unnecessary; visitation is safe with proper labeling. The implant type determines protocol, requiring clear hazard communication.

Question 4

A 58-year-old patient with a massive intracerebral hemorrhage is declared brain dead. The family asks the nurse, "Could his organs help someone else?" while tearfully discussing his undocumented wish to be a donor. Which action aligns with the Organ Procurement Organization (OPO) protocol?

  • A) A) Provide brochures about donation and ask if they'd like to speak to the OPO coordinatorโœ“
  • B) B) Contact the OPO immediately since brain death confirms donation eligibility
  • C) C) Explain that the patient's undocumented wishes cannot be honored without family consent
  • D) D) Consult the hospital ethics committee before initiating donation discussions
Show rationale

OPO protocols require trained coordinators to handle donation discussions. The nurse's role is to provide basic information and facilitate OPO contact without coercion. Option B oversteps by initiating contact without family readiness. Option C inaccurately implies undocumented wishes are irrelevant; families can still consent. Option D delays time-sensitive processes unnecessarily. Brain death establishes medical eligibility, but family emotional readiness (tearfulness) necessitates a non-coercive approach per United Network for Organ Sharing guidelines.

Question 5

A 72-year-old with end-stage heart failure (ejection fraction 25%) and anemia (Hb 9.0 g/dL) reports profound fatigue limiting self-care. Oxygen saturation is 94% on room air. The nurse notes the patient tires after 5 minutes of activity. Which intervention addresses fatigue most effectively?

  • A) A) Initiate a supervised aerobic exercise program three times weekly
  • B) B) Administer prescribed intravenous iron sucrose infusion promptly
  • C) C) Teach energy conservation techniques with activity pacingโœ“
  • D) D) Increase dietary protein intake to 1.5 g/kg/day immediately
Show rationale

Energy conservation is foundational for fatigue in advanced illness. Exercise (A) risks overexertion with severe heart failure. IV iron (B) corrects anemia but takes weeks for effect. Protein increase (D) may help cachexia but doesn't address acute fatigue. Cues: extreme deconditioning (tiring in 5 minutes) and stable oxygen saturation prioritize non-pharmacologic management per palliative care standards.

Question 6

A 70-year-old with peritoneal carcinomatosis reports constant nausea and fatigue. Exam shows ascites and dry mucous membranes. The nurse should anticipate which combination therapy?

  • A) A) Scheduled scopolamine patch and IV fluid bolus
  • B) B) PRN lorazepam and salt-restricted diet
  • C) C) Scheduled octreotide and therapeutic paracentesisโœ“
  • D) D) PRN promethazine and high-carbohydrate meals
Show rationale

Octreotide reduces secretion-related nausea in carcinomatosis; paracentesis alleviates ascites-induced fatigue. Scopolamine (A) may worsen dry mouth. Lorazepam (B) targets anxiety nausea, not ascites. Promethazine (D) is sedating, exacerbating fatigue. Cues: ascites and dehydration signs indicate mechanical contributors requiring dual symptom control per NCCN guidelines.

Question 7

A hospice nurse notes a terminally ill patient has new onset of loud, gurgling respirations. The patient is comatose with absent corneal reflexes and irregular pulse (48/min). Which intervention is both effective for symptom management and consistent with imminent death care priorities?

  • A) A) Administer IV atropine to reduce secretions
  • B) B) Initiate nasopharyngeal suctioning every 30 minutes
  • C) C) Position laterally with slight head elevationโœ“
  • D) D) Start high-flow oxygen via non-rebreather mask
Show rationale

Lateral positioning promotes drainage of oropharyngeal secretions, reducing "death rattle" without invasive measures. Option A is suboptimal as IV access is often discontinued in active dying; subcutaneous glycopyrrolate is preferred. Option B causes discomfort without clearing deep secretions. Option D increases dryness without benefit when hypoxemia is expected. CMSRN guidelines prioritize non-invasive comfort measures for respiratory secretions in unconscious patients near death.

Question 8

After a 45-year-old donor's organs are recovered in the OR, the spouse tells the nurse, "I need to see him without all those tubes now." Which response prioritizes both bereavement care and tissue donation integrity?

  • A) A) Prepare the body by removing medical devices and covering surgical sites per OPO instructionsโœ“
  • B) B) Escort the family to the OR immediately to view the body before transport
  • C) C) Explain that surgical incisions make viewing inappropriate to preserve dignity
  • D) D) Delay viewing until the funeral home prepares the body to avoid family distress
Show rationale

OPO protocols include post-recovery body preparation to facilitate viewing while maintaining dignity. Immediate OR viewing (B) risks exposing the family to traumatic sights and disrupts sterile processes. Denying viewing (C) disregards bereavement needs; covering incisions allows respectful closure. Delaying to funeral homes (D) may prolong grief without cause; nurses can prepare bodies per OPO standards. Covering surgical sites balances emotional needs with ethical obligations.

Question 9

A 70-year-old with advanced heart failure (NYHA Class IV) has frequent hospitalizations. The cardiologist estimates a prognosis of 8 months. The patient wishes to avoid future hospitalizations but continue diuretics and cardiac medications. Which care model prioritizes symptom control without requiring treatment discontinuation?

  • A) A) Hospice care with home nursing for comfort measures
  • B) B) Palliative care coordinating home-based supportโœ“
  • C) C) Skilled nursing facility for 24-hour clinical oversight
  • D) D) Cardiac rehabilitation for exercise optimization
Show rationale

Palliative care manages symptoms and aligns care with goals (avoiding hospitalizations) while allowing ongoing disease-directed treatments (diuretics). Hospice (A) typically requires โ‰ค6-month prognosis and focuses solely on comfort. Skilled nursing (C) provides acute care, not symptom-focused support. Rehabilitation (D) is inappropriate for end-stage functional decline. Prognosis exceeding 6 months and desire for continued treatment are key cues per CMS guidelines.

Question 10

A patient with metastatic cancer becomes agitated, plucking at bed linens and moaning. Vital signs show BP 90/60, temp 38.5ยฐC (101.3ยฐF), and irregular pulse. Which assessment finding most reliably differentiates terminal restlessness from delirium requiring medical intervention?

  • A) A) Diaphoresis with mottled extremitiesโœ“
  • B) B) Disorientation to time and place
  • C) C) Elevated temperature with dry mucous membranes
  • D) D) Visual hallucinations reporting deceased relatives
Show rationale

Diaphoresis + mottling confirm terminal physiological decline, making restlessness an imminent death sign. Option B/C/D suggest reversible delirium: disorientation may indicate infection/medication toxicity, fever requires evaluation for sepsis, and hallucinations could stem from electrolyte imbalances. Per CMSRN protocols, concurrent signs of multisystem failure (mottling, hypotension) differentiate terminal agitation from treatable delirium.

Question 11

A hospice nurse visits a home and finds a terminal lung cancer patient deceased. The spouse reports the patient fell the previous night but refused hospital care. An untreated 5-cm hematoma is visible on the occiput. Which action aligns with coroner protocols?

  • A) A) Advise the spouse to call funeral home directly for body removal
  • B) B) Document the injury and notify the hospice physician for pronouncement
  • C) C) Contact the coroner due to unexplained trauma before deathโœ“
  • D) D) Provide grief support and complete routine post-mortem care
Show rationale

Unexplained trauma (hematoma cue) in non-hospitalized patients requires coroner notification per statutory guidelines. Option C addresses this. Option A ignores potential forensic evidence. Option B is insufficient; coroners override hospice protocols for traumatic deaths. Option D neglects legal obligations despite palliative context.

Question 12

A 72-year-old patient with metastatic lung cancer admitted for pneumonia has a living will specifying no intubation. During a sudden respiratory arrest, the spouse insists the patient "would want everything done." The patient is unresponsive. What is the nurse's priority action?

  • A) A) Initiate CPR immediately while clarifying the spouse's statements
  • B) B) Honor the living will by withholding resuscitation measuresโœ“
  • C) C) Contact the hospital ethics committee for emergency guidance
  • D) D) Defer to the spouse's request as the legal next of kin
Show rationale

The living will is a legally binding document reflecting the patient's autonomous wishes, which take precedence over family requests in emergencies. Option B aligns with ethical principles of autonomy and legal requirements for advance directives. Option A violates the patient's explicit directive. Option C delays time-sensitive care and isn't feasible during arrest. Option D disregards the legal standing of the living will. Nurses must act on valid advance directives per the Patient Self-Determination Act, even with family objections.

Question 13

An alert lung cancer patient with dyspnea during conversation reports panic with activity. Palliative Performance Scale is 50%. Which non-pharmacological intervention demonstrates the strongest evidence for dyspnea relief?

  • A) A) Instruct pursed-lip breathing techniques
  • B) B) Provide mindfulness meditation recording
  • C) C) Apply cool cloth to the forehead
  • D) D) Use a handheld fan directed toward faceโœ“
Show rationale

Fan therapy stimulates trigeminal nerve receptors, reducing dyspnea perception with immediate effect, supported by Cochrane reviews. Pursed-lip breathing (A) benefits COPD but not restrictive malignancies. Meditation (B) requires practice time inconsistent with acute panic. Cool cloths (C) offer comfort but lack dyspnea-specific evidence. The fan's rapid response aligns best with activity-triggered panic and preserved cognition.

Question 14

An alert 65-year-old with end-stage heart failure requests DNR status, but her daughter insists on "full code" during a family meeting. The patient tells the nurse privately, "I'm ready to go peacefully." What is the nurse's priority action?

  • A) A) Advocate for the patient's stated wishes with the healthcare team and daughterโœ“
  • B) B) Defer to the daughter's preference since family consensus is required
  • C) C) Suggest a psychiatric consult to assess the patient's decision-making capacity
  • D) D) Delay documentation until the ethics committee resolves the conflict
Show rationale

Option A prioritizes the alert patient's autonomy (cue 1) and private disclosure (cue 2). Competent patients have legal authority over code decisions, requiring nurse advocacy per palliative care standards. Option B disregards self-determination. Option C is unwarranted without evidence of incapacity. Option D delays fulfilling ethical obligations. Nurses must champion patient preferences even during family disagreements, as per AMSN advocacy principles.

Question 15

During end-of-life care, a family declines organ donation due to religious concerns but asks about tissue donation. How should the nurse proceed?

  • A) A) Honor the refusal since both processes are linked ethically
  • B) B) Explain tissue donation remains possible and contact the OPOโœ“
  • C) C) Suggest corneal donation only to align with religious views
  • D) D) Document refusal without further discussion per autonomy
Show rationale

Organ and tissue donation are separate consents; declining one doesn't preclude the other. Option A misrepresents regulations. Option C assumes religious compatibility without assessment; OPOs handle nuanced discussions. Option D neglects therapeutic communication; nurses should clarify options without pressure. Religious objections often vary by donation type, warranting OPO consultation for culturally sensitive education.

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An 82-year-old with advanced dementia hospitalized for dehydration has a valid DPOA-HC designating a niece as โ€ฆ

A) A) Advocate for the niece's decision sin
B) B) Refuse the feeding tube based on the
C) C) Clarify the niece's rationale and rep
D) D) Defer to the physician's judgment reg
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