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FNP Low Back Pain Practice Questions

Most low back pain resolves without imaging, which is exactly why the exam tests whether you can spot the cases that are different. These questions cover the red flags that change management, when imaging is genuinely indicated, evidence-based conservative treatment, and what to tell a patient about staying active.

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  • 📖 Full rationales — why every option is right or wrong

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Written and reviewed by the LexPort exam-prep team, led by our Founder & Exam-Prep Lead. LexPort builds certification practice questions — this is exam-preparation material, not medical advice. Last reviewed September 2026.

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Test yourself: Low Back Pain

Three FNP practice questions on low back pain — tap an answer for instant feedback. The app has 3,000+, timed and scored.

Question 1

A patient reports moderate back pain and receives an oral dose of oxycodone. The nurse practitioner is planning the follow-up evaluation. To accurately capture the peak effect of this medication, when should the practitioner reassess the numeric pain rating scale?

Why A is the answer

The peak effect of oral analgesics generally occurs around sixty minutes, making this the optimal time to evaluate efficacy. Option B is too early, as fifteen minutes is appropriate for intravenous medications but not oral ones. Options C and D are too late, as the peak plasma concentration will have already passed, potentially leading to an inaccurate assessment of the medication's maximum benefit. Waiting two to four hours might result in the patient experiencing recurrent pain before the next dose is due.

🔑 Key takeaway

Oral analgesics typically reach their peak effect around sixty minutes post-administration.

Question 2

A 22-year-old runner presents with a painful, hyperkeratotic plantar wart on the left heel. Prior to applying cryotherapy, which action is most appropriate?

Why A is the answer

Plantar warts feature thick overlying hyperkeratosis that heavily insulates the underlying infected tissue. You must pare the callus with a surgical blade until pinpoint bleeding occurs to allow the liquid nitrogen to penetrate effectively. Injecting local anesthetic is unnecessarily painful and rarely required for standard cryotherapy. Applying silver nitrate is a separate destructive modality, not a preparatory step for freezing. Soaking the foot in chlorhexidine does not remove the physical keratin barrier blocking the cold transfer.

🔑 Key takeaway

Paring hyperkeratotic tissue on plantar warts is essential before cryotherapy to ensure adequate freezing depth.

Question 3

A 35-year-old patient with suspected rotator cuff tendinopathy returns after twelve weeks of targeted physical therapy. The patient reports complete pain resolution but demonstrates persistent weakness against resistance during active abduction. What is the most appropriate next step?

Why D is the answer

When evaluating physical therapy outcomes, a lack of strength improvement after an adequate trial suggests a structural deficit rather than simple tendinopathy. Persistent weakness despite twelve weeks of therapy strongly points to a full-thickness rotator cuff tear, making an MRI the most appropriate next step to guide potential surgical intervention. Discharging the patient ignores the unresolved functional deficit. Administering a corticosteroid injection is inappropriate because the patient is already pain-free, and steroids do not fix structural weakness. Advising complete rest will likely lead to further muscle atrophy and joint stiffness.

🔑 Key takeaway

Persistent weakness after adequate physical therapy for a rotator cuff injury suggests a structural tear requiring imaging.

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Question 1

A 70-year-old female receives a dual-energy X-ray absorptiometry (DEXA) scan. The report indicates a T-score of -1.9 at the hip and a T-score of -2.6 at the lumbar spine. She has no history of fractures or secondary causes of bone loss. How should this patient's bone health be classified?

  • A) Primary osteopenia diagnostic category
  • B) Secondary osteopenia diagnostic category
  • C) Primary osteoporosis diagnostic category
  • D) Secondary osteoporosis diagnostic category

💡 Key Takeaway

Bone mineral density diagnosis is determined by the lowest T-score at any valid skeletal site.

Show rationale

The diagnosis of bone mineral density disorders is always based on the lowest T-score obtained from any valid skeletal site. Although this patient has a T-score of -1.9 at the hip, which falls into the osteopenia range, her lumbar spine T-score is -2.6. This lower value meets the diagnostic criteria for osteoporosis (T-score of -2.5 or below). Primary osteopenia diagnostic category is incorrect because the more severe spine score overrides the hip score in clinical decision-making. Secondary osteopenia diagnostic category is incorrect as there are no secondary causes mentioned, and the lowest score indicates osteoporosis rather than osteopenia. Secondary osteoporosis diagnostic category is incorrect because there is no evidence of a secondary etiology like medication-induced bone loss. Therefore, primary osteoporosis is the correct and most accurate diagnostic category.

Question 2

A 29-year-old male complains of low back pain after moving furniture. He has had symptoms present for 5 days and exhibits high anxiety about permanent damage. His physical and neurologic examinations are completely normal.

  • A) Order a lumbar MRI to provide reassurance.
  • B) Explain the favorable prognosis of acute pain.
  • C) Refer immediately to a pain management specialist.
  • D) Prescribe a rigid lumbar brace for daily use.

💡 Key Takeaway

Patient education and reassurance about the favorable natural history of acute low back pain are essential non-pharmacologic interventions.

Show rationale

Providing reassurance about the favorable prognosis is a critical, evidence-based non-pharmacologic intervention that directly addresses patient anxiety and improves outcomes. Most acute low back pain resolves within a few weeks regardless of treatment. Ordering an MRI (A) for reassurance is contraindicated in the absence of red flags and often leads to unnecessary interventions. A pain management referral (C) is premature for a 5-day history of uncomplicated pain. A rigid lumbar brace (D) promotes muscle deconditioning and is not recommended for acute mechanical back pain.

Question 3

A 40-year-old construction worker presents with acute low back pain and visible paravertebral muscle spasms after lifting a heavy crate. The neurological examination reveals no neurologic deficits. Which short-term pharmacological intervention is most appropriate?

  • A) Prescribe a short course of oral pregabalin
  • B) Prescribe a short course of oral tramadol
  • C) Prescribe a short course of oral cyclobenzaprine
  • D) Prescribe a short course of oral duloxetine

💡 Key Takeaway

Non-benzodiazepine muscle relaxants are indicated for short-term relief of acute low back pain complicated by muscle spasms.

Show rationale

Clinical guidelines recommend NSAIDs or skeletal muscle relaxants like cyclobenzaprine for acute, non-radicular low back pain with prominent muscle spasms. Pregabalin and duloxetine are indicated for chronic or neuropathic pain conditions, not acute mechanical back injuries. Tramadol is an opioid analgesic and is not recommended as a first-line treatment for acute musculoskeletal pain due to the risk of dependence and side effects.

Question 4

A 65-year-old healthy woman undergoes her first screening DEXA scan. The results demonstrate a T-score of -0.8 at the lumbar spine and a T-score of -0.9 at the femoral neck. What is the most accurate interpretation?

  • A) Interpret results as normal density for age.
  • B) Interpret results as mild osteopenia needing changes.
  • C) Interpret results as borderline osteoporosis needing monitoring.
  • D) Interpret results as low mass needing supplements.

💡 Key Takeaway

A T-score of -1.0 or higher at all measured sites indicates normal bone density and requires no medical intervention.

Show rationale

A T-score of -1.0 or higher at all measured sites is classified as normal bone density according to World Health Organization criteria. Since her lowest T-score is -0.9, she does not meet the diagnostic criteria for osteopenia or osteoporosis. Options B and D are incorrect because osteopenia, also known as low bone mass, requires a T-score strictly between -1.0 and -2.5. Option C is incorrect because osteoporosis requires a T-score of -2.5 or lower, making borderline osteoporosis an inaccurate clinical interpretation.

Question 5

A 45-year-old male presents with a 6-month history of non-radicular lower back pain. He reports avoiding all physical activity due to fear of worsening the damage and scores highly on the Pain Catastrophizing Scale. Which non-pharmacologic intervention is most appropriate?

  • A) Initiate cognitive behavioral therapy
  • B) Prescribe supervised exercise therapy
  • C) Recommend spinal manipulative therapy
  • D) Order intermittent lumbar traction

💡 Key Takeaway

Cognitive behavioral therapy effectively addresses maladaptive coping and fear-avoidance in chronic back pain.

Show rationale

This patient exhibits significant fear-avoidance behavior and catastrophizing, making cognitive behavioral therapy the most appropriate intervention. CBT helps reframe maladaptive thoughts and improves functional outcomes in chronic pain. While supervised exercise therapy is generally a first-line treatment for chronic lower back pain, this patient's severe fear-avoidance will likely prevent adherence until the psychological barrier is addressed. Spinal manipulative therapy offers modest benefits for pain but does not actively modify the underlying catastrophic pain beliefs. Intermittent lumbar traction is not recommended by current clinical guidelines for chronic lower back pain due to a lack of proven efficacy. Addressing the psychological components of pain is essential before or alongside physical interventions.

Question 6

A 50-year-old construction worker reports persistent lower back pain despite 12 weeks of physical therapy. He feels depressed, is unable to return to his construction job, and requests further non-pharmacologic options. Which intervention is most appropriate?

  • A) Isolated spinal manipulation therapy
  • B) Mindfulness based stress reduction
  • C) Multidisciplinary biopsychosocial rehabilitation
  • D) Transcutaneous electrical nerve stimulation

💡 Key Takeaway

Multidisciplinary rehabilitation is indicated for chronic back pain failing initial therapies with significant occupational impact.

Show rationale

When a patient experiences persistent pain that fails standard single-modality treatments and results in significant occupational impairment, a multidisciplinary biopsychosocial rehabilitation program is the most effective approach. This method combines physical, psychological, and occupational therapies to address complex pain presentations. Isolated spinal manipulation therapy is unlikely to succeed given the failure of previous physical therapy and the new depressive symptoms. Mindfulness based stress reduction is an excellent adjunct for chronic pain but does not provide the comprehensive physical and vocational support needed for a return to heavy labor. Transcutaneous electrical nerve stimulation is generally not recommended by clinical guidelines for chronic lower back pain due to insufficient evidence of long-term benefit.

Question 7

A 30-year-old female with chronic daily prednisone use for systemic lupus reports sudden back pain after coughing. Which underlying diagnosis does this subjective history most strongly suggest?

  • A) Acute severe lumbar muscle strain
  • B) Herniated lumbar intervertebral disc injury
  • C) Osteoporotic vertebral body compression fracture
  • D) Inflammatory sacroiliac joint dysfunction process

💡 Key Takeaway

Chronic steroid use predisposes young adults to osteoporotic compression fractures from minor mechanical stressors.

Show rationale

Long-term corticosteroid use is a major risk factor for secondary osteoporosis, even in young adults. A sudden onset of back pain following a minor mechanical stressor like coughing strongly points to an osteoporotic fracture. Option A is possible but less likely to be triggered purely by coughing without a history of heavy lifting or twisting. Option B can be exacerbated by coughing due to increased intraspinal pressure, but the chronic steroid use makes a fracture the primary red flag to rule out first. Option D presents with insidious, chronic pain rather than sudden, acute pain from a minor event. Identifying medication-induced bone demineralization as a risk factor is essential when obtaining subjective history for acute back pain.

Question 8

A 78-year-old female reports bilateral posterior leg pain that occurs after walking one block. She notes the pain is relieved by leaning forward on her shopping cart but is not by standing still. Her pedal pulses are 2+ bilaterally. Which is the most likely primary diagnosis?

  • A) Aortoiliac peripheral arterial disease.
  • B) Lumbar spinal canal stenosis.
  • C) Chronic deep venous insufficiency.
  • D) Small fiber peripheral neuropathy.

💡 Key Takeaway

Leg pain relieved by lumbar flexion rather than simple rest strongly suggests neurogenic claudication over vascular claudication.

Show rationale

This patient's presentation is classic for neurogenic claudication caused by lumbar spinal stenosis. The key distinguishing feature is that her pain is relieved by lumbar flexion (the "shopping cart sign") rather than just resting, whereas true vascular claudication from peripheral arterial disease is promptly relieved by simply standing still. Aortoiliac disease would present with buttock or thigh pain relieved by standing. Chronic deep venous insufficiency typically causes a heavy, aching sensation accompanied by edema that worsens dependently, rather than exertional pain. Small fiber peripheral neuropathy presents with burning, tingling, or numbness that is often worse at night and is not strictly tied to exertion.

Question 9

A 30-year-old construction worker reports severe lower back pain after twisting awkwardly on the job site. He describes a burning pain radiating to the dorsum of his right foot. During the physical examination, the clinician notes diminished sensation over the dorsal aspect of the right foot and weakness with right great toe extension. His patellar and Achilles reflexes are bilaterally symmetric and intact. Which diagnosis best explains these specific clinical findings?

  • A) Acute mechanical lumbar strain
  • B) S1 nerve root radiculopathy
  • C) L4 nerve root radiculopathy
  • D) L5 nerve root radiculopathy

💡 Key Takeaway

L5 radiculopathy is characterized by pain radiating to the foot dorsum and weakness in great toe extension.

Show rationale

The patient's presentation of burning pain radiating specifically to the dorsum of the foot, combined with weakness with right great toe extension, specifically localizes the lesion to an L5 nerve root radiculopathy. An acute mechanical lumbar strain would not produce these distinct motor and sensory deficits, as it typically presents with localized paraspinal muscle spasms. An S1 nerve root radiculopathy typically affects the lateral aspect of the foot and plantar flexion, often presenting with an absent Achilles reflex, which is intact in this patient. An L4 nerve root radiculopathy usually involves the medial lower leg and a diminished patellar reflex. Accurately mapping dermatomal and myotomal deficits allows the clinician to confidently differentiate specific radiculopathies from generalized mechanical back pain.

Question 10

A 16-year-old male reports constant, severe nocturnal back pain that awakens him. The Adams forward bend test is negative for any rib hump or asymmetry. What is the most appropriate next step?

  • A) Reassure him that adolescent growth pains are entirely normal.
  • B) Recommend daily nonsteroidal anti-inflammatory medications and gentle back stretching.
  • C) Order advanced imaging to evaluate for underlying spinal pathology.
  • D) Apply a scoliometer to precisely measure the trunk rotation.

💡 Key Takeaway

Severe nocturnal back pain in adolescents is a red flag requiring advanced imaging, regardless of scoliosis screening results.

Show rationale

The correct answer is C. Adolescent idiopathic scoliosis is classically painless. When an adolescent presents with constant, severe nocturnal back pain that awakens them from sleep, it is a significant red flag that warrants immediate advanced imaging to rule out underlying spinal pathology, such as an osteoid osteoma, infection, or malignancy. A negative Adams forward bend test effectively rules out a significant structural scoliosis but does not explain the severe pain. Reassuring the patient that this is normal growth pain (Option A) is dangerous and ignores a critical warning sign. Recommending NSAIDs and stretching (Option B) provides only symptomatic relief without investigating the alarming nocturnal presentation. Applying a scoliometer (Option D) is futile and inappropriate given that the forward bend test is already negative for any visible rotational asymmetry or rib hump.

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FNP · Exam Simulator

A 70-year-old female receives a dual-energy X-ray absorptiometry (DEXA) scan. The report indicates a T-score o…

A) Primary osteopenia diagnostic category
B) Secondary osteopenia diagnostic category
C) Primary osteoporosis diagnostic category
D) Secondary osteoporosis diagnostic catego
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